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Valerie performed her graduate work in the laboratory of Marc Parmentier at Université Libre de Bruxelles (ULB) where she identified chemerin as the endogenous ligand of the orphan G protein-coupled receptor ChemR23. For this work, she was awarded the Belgian Galien Prize of Pharmacology in 2006.

She then joined the laboratory of David Traver at University of California at San Diego (UCSD) where she developed novel zebrafish transgenic lines that provided new insights into the cellular biology of the zebrafish hematopoietic system.

She moved back to Belgium in 2013 after being awarded a Brains Back to Brussels grant from Innoviris and the Brussels-Capital Region, and obtained a permanent position from the FNRS in 2014. 

Since starting her own laboratory, Valerie has been awarded several competitive grants, including a Welbio Starting Grant in 2015, a FNRS-Large equipment in 2017, a FNRS-MIS in 2018 and an ARC Consolidator grant in 2020. 

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